Everwrinkle V

PLLA injectable material guide

Everwrinkle V

Everwrinkle V is the higher-content model in the Everwrinkle line of poly-L-lactic acid (PLLA) injectable materials made by PharmaResearch, registered separately from the standard Everwrinkle model with double the PLLA content per box.

Published Last updated Medically reviewed by Duk-ha Kim
Maker
PharmaResearch
Registered model
Everwrinkle V — model M13-002
Main ingredient
Poly-L-lactic acid (PLLA), 100 mg
Stated intended use
Temporary improvement of nasolabial folds (nose-to-mouth lines)

What is Everwrinkle V?

Everwrinkle V is a poly-L-lactic acid (PLLA) injectable material made by PharmaResearch, registered as model M13-002 in the company Everwrinkle product line. It sits alongside the standard Everwrinkle model (M13-001) as a separately listed, higher-content version.

Abstract editorial visualization for Everwrinkle V consultation planning
Sources: Abijou editorial visualization (AI-generated)Explanatory AI-generated illustration; not an actual patient photograph.

Sources: Everwrinkle — official product site, models, composition and stated intended use

Who makes Everwrinkle V, and where does the information on this page come from?

PharmaResearch is the manufacturer. Everything on this page — the model numbers, ingredient list and stated intended use — comes from the official Everwrinkle product site, which is the single source used for this guide.

Sources: Everwrinkle — official product site, models, composition and stated intended use

How many Everwrinkle models are officially registered, and what separates them?

The official listing names two separate models: Everwrinkle (M13-001) and Everwrinkle V (M13-002). They share the same PLLA-based composition category but are listed as distinct models rather than one product sold in two sizes.

Sources: Everwrinkle — official product site, models, composition and stated intended use

What does the letter "V" in the product name actually mean?

Per the official model listing, M13-001 (Everwrinkle) contains 50 mg of PLLA with a total of 121.7 mg per box, while M13-002 (Everwrinkle V) contains 100 mg of PLLA with a total of 243.4 mg per box. One letter in the product name corresponds to double the PLLA content — that distinction, not the letter itself, is the fact worth carrying into a consultation.

Sources: Everwrinkle — official product site, models, composition and stated intended use

What is PLLA, the main ingredient in both models?

Both models are based on poly-L-lactic acid (PLLA), listed as the main ingredient in the official composition. The models differ in how much PLLA each contains, not in the ingredient category itself.

Sources: Everwrinkle — official product site, models, composition and stated intended use

What else is in the formulation besides PLLA?

The official listing names carboxymethylcellulose (CMC) and mannitol alongside PLLA in both models. The ingredient categories match between the two models; the milligram amounts and the resulting total weight per box are what differ.

Sources: Everwrinkle — official product site, models, composition and stated intended use

What device category is Everwrinkle listed under?

The product is listed under the device category name "tissue-repair material." This is a category label, not a statement about how quickly or how long a specific result appears.

Sources: Everwrinkle — official product site, models, composition and stated intended use

What is the stated intended use for Everwrinkle and Everwrinkle V?

The official listing states the intended use as the temporary improvement of nasolabial folds (nose-to-mouth lines). Bring this exact wording to a consultation and confirm that the planned treatment area matches it.

Sources: Everwrinkle — official product site, models, composition and stated intended use

Why does PLLA content in milligrams matter more than the product name?

Because the same product family already uses one letter to separate a 50 mg model from a 100 mg model, a name or brand alone does not indicate how much PLLA is being used. Reading the milligram content on the box or in the consultation notes is the reliable way to know what is actually being received.

Sources: Everwrinkle — official product site, models, composition and stated intended use

How should you compare Everwrinkle V with other PLLA-based products?

PLLA content and the accompanying ingredients vary across products and brands, so comparing by product name or by vial count is not reliable. Compare by milligrams of PLLA per unit and by the total formulation, and confirm those figures for whichever product is being discussed.

Sources: Everwrinkle — official product site, models, composition and stated intended use

What happens during an Everwrinkle V treatment session?

A licensed clinician reconstitutes the product and injects it into the treatment area. The official source does not publish a session protocol beyond the composition and stated use, so ask the treating clinic to walk through its own procedure and confirm which model is being used.

Sources: Everwrinkle — official product site, models, composition and stated intended use

How do you read a quotation that is based on dosage rather than sessions?

Because the two models are separated by content rather than by a session count, a quotation is easier to compare when it states the model, the total PLLA milligrams used and the dilution, rather than a single session price. Ask the clinic to itemize the quotation this way before comparing it with an offer from another clinic.

Sources: Everwrinkle — official product site, models, composition and stated intended use

How do you confirm the treatment area matches the stated use?

The stated intended use names nasolabial folds specifically. If a different area is being discussed, ask the clinic directly whether that area falls within the stated use for the model being planned.

Sources: Everwrinkle — official product site, models, composition and stated intended use

How long does the effect last?

The official Everwrinkle source used on this page states the intended use as "temporary improvement of nasolabial folds" — it does not publish a duration figure in months or years for either model, so no number from this source can be quoted as how long a result holds. What is documented is that the two models differ by PLLA content (50 mg for Everwrinkle, 100 mg for Everwrinkle V), and that PLLA-based collagen-stimulating injectables as a class work by prompting the body’s own response over time rather than by holding physical volume in place, which is why this page already treats delayed nodules as a class-level consideration rather than an isolated event. How long a change holds up is more a function of which model and PLLA dose was used, the treatment area, and individual response than a single figure this source provides. Ask the clinic which model is planned, the total PLLA milligrams and dilution, and how it decides when a repeat session might be considered.

Sources: Everwrinkle — official product site, models, composition and stated intended use

What safety considerations apply across PLLA-class injectables?

PLLA-based collagen-stimulating injectables as a category can involve delayed reactions such as nodules, which this site Sculptra guide discusses in more detail with its own sourcing. That is a class-level consideration rather than data specific to Everwrinkle V, and the official Everwrinkle source used for this page does not itself publish adverse-reaction figures.

Sources: Everwrinkle — official product site, models, composition and stated intended use

What should you confirm at the consultation before treatment?

Confirm which model is planned — Everwrinkle (50 mg) or Everwrinkle V (100 mg) — along with the dilution method and total volume, whether the treatment area matches the stated intended use, and the clinic plan for monitoring and managing a nodule if one appears.

Sources: Everwrinkle — official product site, models, composition and stated intended use

Who should administer an Everwrinkle V treatment?

Only a licensed medical professional trained in reconstituting and injecting PLLA-based materials should perform the treatment. Ask who will inject, which model they plan to use, and how they would respond if a delayed nodule occurred.

Sources: Everwrinkle — official product site, models, composition and stated intended use

How do the two registered Everwrinkle models compare?

These two models are not interchangeable sizes of the same product — they are separately registered models with different PLLA content. Confirm the model name and number rather than assuming which one is being used.

How do the two registered Everwrinkle models compare?
ModelPLLA contentOther listed ingredientsTotal weight per box
Everwrinkle (M13-001)50 mgCMC, mannitol121.7 mg
Everwrinkle V (M13-002)100 mgCMC, mannitol243.4 mg

This table lists the officially registered composition only. It is not a recommendation for one model over the other; the appropriate model depends on clinical assessment.

Sources: Everwrinkle — official product site, models, composition and stated intended use

Medical care at Abijou

Care is provided by the medical team at the branch you select. These clinicians lead the three branches linked from this guide; confirm the doctor assigned to your visit with that branch.

Duk-ha Kim Chief MD, Gangnam

Chief MD, Gangnam

Duk-ha Kim

The trust our patients have placed in this clinic was built on conviction and principle. We intend to hold to both, unchanged, through the next hundred years.

Cheol-su Yoon Chief MD, Myeongdong

Chief MD, Myeongdong

Cheol-su Yoon

I want to be thinking about how the patient feels right up to the last moment of the procedure.

Jae-wook Kim Chief MD, Hongdae

Chief MD, Hongdae

Jae-wook Kim

I will give my best with the attentiveness to catch even the smallest change.

Listed branch medical team — not a medical-review byline for this article.

Frequently asked questions

Is Everwrinkle V simply a stronger version of Everwrinkle?

In terms of registered PLLA content, yes — Everwrinkle V (M13-002) lists 100 mg of PLLA against 50 mg for the standard Everwrinkle (M13-001). Both share the same ingredient categories (PLLA, CMC, mannitol) and the same stated intended use; the milligram amount is what the official listing shows as different.

Does "Everwrinkle V" refer to a different treatment area than Everwrinkle?

No — the official listing states the same intended use, temporary improvement of nasolabial folds, without naming a separate area for the V model. The difference the listing documents is PLLA content, not treatment area.

Is PLLA content the only listed difference between the two models?

Based on the official listing, yes — the ingredient categories (PLLA, CMC, mannitol) match between models, and the figures that differ are the PLLA milligrams and the resulting total weight per box.

What is PLLA, the shared main ingredient in both models?

PLLA stands for poly-L-lactic acid, the main ingredient listed for both Everwrinkle and Everwrinkle V. The two models use the same main ingredient at different milligram amounts rather than different ingredients.

What does "tissue-repair material" mean as a device category?

It is the device category name under which Everwrinkle is officially listed. It describes a category, not a specific claim about how quickly or how long an individual result appears.

What is the stated intended use for Everwrinkle and Everwrinkle V?

The official listing states the intended use as the temporary improvement of nasolabial folds (nose-to-mouth lines). Confirm that this matches the area intended for treatment before booking.

Can two PLLA products be compared just by counting vials or sessions?

No — vial count or session number does not indicate PLLA content per unit, and that content varies by product and by model, as it does between Everwrinkle and Everwrinkle V. Compare the milligrams of PLLA and the total formulation instead.

Does this page state how long results last or how many sessions are needed?

No — this page covers the registered composition, device category and stated intended use only. Duration, improvement rate and session count are outside what the official source used here publishes, so ask the treating clinic directly.

Why should you ask specifically which model number was used?

Because "Everwrinkle" and "Everwrinkle V" are two separately registered models with different PLLA content, asking for the model number (M13-001 or M13-002) is more reliable than relying on the product name alone, which is easy to mishear or mistype.

Why does the dilution method matter when comparing quotations?

Because the same PLLA content can be reconstituted with different amounts of diluent, the dilution method and total volume affect what a given quotation actually represents. Ask the clinic to state the model, the PLLA milligrams and the dilution together before comparing prices between clinics.

How do you check whether the treatment area matches the stated use?

Ask the clinic to confirm, at the consultation, that the planned injection area is the nasolabial fold area named in the stated intended use. If a different area is being discussed, ask directly whether that use is documented for the model being planned.

Are nodules a consideration with PLLA-class products like Everwrinkle V?

Yes — nodules are a reaction associated with PLLA-based collagen-stimulating injectables as a category, and this site Sculptra guide discusses that class-level consideration with its own sourcing. The official Everwrinkle source used for this page does not itself publish adverse-reaction figures for Everwrinkle V specifically.

What should happen if a nodule appears after treatment?

Contact the treating clinic rather than waiting for it to resolve on its own. Agreeing on a follow-up and contact plan with the clinic before treatment is one of the consultation items this page recommends.

Who should administer an Everwrinkle V treatment?

Only a licensed medical professional trained in reconstituting and injecting PLLA-based materials should perform it. Confirm who will inject, which model they plan to use, and how they would manage a delayed nodule if one occurred.

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