Seoul
Chief MD, Gangnam
Duk-ha Kim
The trust our patients have placed in this clinic was built on conviction and principle. We intend to hold to both, unchanged, through the next hundred years.
Injectable skin-quality guide
Rejuran Healer
Rejuran is an injectable medical device containing polynucleotide (PN), intended for temporary improvement of facial wrinkles — not a hyaluronic-acid filler and not a promise of tissue regeneration.
- Material
- Polynucleotide (PN), salmon-derived
- Stated purpose
- Temporary improvement of facial wrinkles
- Product lineup
- Classic, i, s, HB plus — not interchangeable
- Evidence note
- Reviewed sources lack a complete Korean-specific IFU; ask the clinic to show it
What is Rejuran Healer?
Rejuran is an injectable medical device containing polynucleotide (PN), intended for temporary improvement of facial wrinkles.
Sources: REJURAN basic product (PN) · PharmaResearch officialREJURAN · TGA ARTG 412630
What is Rejuran made of?
Its principal material is salmon-derived PN manufactured with PharmaResearch’s DOT technology. The manufacturer describes PN as being placed into the dermis. It is not a conventional volumizing HA filler, and no source reviewed here supports a tissue-regeneration claim.
Sources: REJURAN basic product (PN) · PharmaResearch officialREJURAN lineup, HB plus formulation · PharmaResearch press
Which products are in the Rejuran lineup?
Classic, i, s and HB plus are distinct products in the PN-based Rejuran lineup. HB plus also contains hyaluronic acid and lidocaine. Confirm the exact product and its locally approved use before treatment; the product names alone do not establish which option suits your treatment area.
Sources: REJURAN lineup, HB plus formulation · PharmaResearch pressREJURAN i · PharmaResearch officialREJURAN s · PharmaResearch officialREJURAN HB plus · PharmaResearch official
What should you ask at the consultation?
Ask which exact Rejuran product is proposed, why it suits the treatment area, what the locally approved indication is, who will inject it, and which product-specific contraindications and adverse reactions appear in the local IFU.
Sources: REJURAN basic product (PN) · PharmaResearch officialREJURAN lineup, HB plus formulation · PharmaResearch pressREJURAN i · PharmaResearch officialREJURAN s · PharmaResearch officialREJURAN HB plus · PharmaResearch official
How is a Rejuran treatment plan decided?
After medical assessment, the clinician selects the product and treatment area and administers multiple injections according to the locally approved IFU. Dose, depth, number of injection points and session schedule must be individualized.
Sources: REJURAN lineup, HB plus formulation · PharmaResearch press
How long does the effect last?
How long the effect lasts depends on which product is used and how quickly your body processes the injected material. PN is placed into the dermis and is not intended to sit as a static volumizing gel, so it does not behave like an HA filler over time; the manufacturer pages reviewed here list classic, i, s and HB plus as separate formulations without stating a shared duration figure for any of them. Course design also affects what you feel — clinics commonly run Rejuran as a series of sessions rather than a single visit, and that schedule affects when you would judge the result. Ask your clinic which product is planned, how many sessions the local IFU recommends for your treatment area, and at what interval they suggest a repeat session; that answer should come from the locally approved instructions, not from the product name alone.
Sources: REJURAN lineup, HB plus formulation · PharmaResearch press
What do the sources say about short-term reactions?
Injection discomfort can occur; the manufacturer notes that PN’s molecular weight and viscosity can contribute to pain. Ask the clinic for the complete product-specific reaction list from the local IFU, since the public pages reviewed here do not include one.
Sources: REJURAN lineup, HB plus formulation · PharmaResearch press
How is eligibility for Rejuran decided?
Eligibility must be determined from medical history and the exact local IFU. The public manufacturer pages reviewed do not provide a complete contraindication list; HB plus additionally contains hyaluronic acid and lidocaine, which must be included in allergy screening.
When should you contact the clinic?
Contact the treating clinic promptly for unexpected, worsening or persistent symptoms, and seek emergency care for any medical emergency. A product-specific emergency symptom list should come from the locally supplied IFU rather than another injectable’s list.
Where does Rejuran sit among injectables?
Rejuran is PN-based and positioned for temporary facial-wrinkle improvement. HA fillers are gels that smooth or fill by combining with water and adding volume; Sculptra contains PLLA and is administered as a series of treatments with a gradual collagen-related effect. They are not interchangeable.
Sources: REJURAN basic product (PN) · PharmaResearch officialSculptra e-IFU (USA) · Galderma
Are Classic, i, s and HB plus interchangeable?
Classic, i, s and HB plus share the same PN base but are not identical. This table lists only differences confirmed on the manufacturer’s own product pages, not spread, viscosity or performance claims that are not published there.
| Product | Confirmed composition | Useful question to ask | Confirm before choosing |
|---|---|---|---|
| Classic | Polynucleotide (PN) | Is broader facial improvement the goal this product is proposed for? | The exact indication and whether it fits your treatment area |
| i | Polynucleotide (PN) | Why is i proposed over Classic or s for this area? | Local approval and the reason it suits your specific area |
| s | Polynucleotide (PN) | Why is s proposed over Classic or i for this area? | Local approval and the reason it suits your specific area |
| HB plus | Polynucleotide (PN) + sodium hyaluronate + lidocaine | Does the added hyaluronic acid or lidocaine change suitability for me? | Your allergy history for hyaluronic acid and lidocaine |
This table lists confirmed composition differences only. PharmaResearch’s public pages do not publish viscosity or spread comparisons between i and s, so this guide does not claim any.
Sources: REJURAN basic product (PN) · PharmaResearch officialREJURAN lineup, HB plus formulation · PharmaResearch pressREJURAN i · PharmaResearch officialREJURAN s · PharmaResearch officialREJURAN HB plus · PharmaResearch official
Medical care at Abijou
Care is provided by the medical team at the branch you select. These clinicians lead the three branches linked from this guide; confirm the doctor assigned to your visit with that branch.
Chief MD, Myeongdong
Cheol-su Yoon
I want to be thinking about how the patient feels right up to the last moment of the procedure.
Chief MD, Hongdae
Jae-wook Kim
I will give my best with the attentiveness to catch even the smallest change.
Listed branch medical team — not a medical-review byline for this article.
Frequently asked questions
Does an overseas registration guarantee Korean approval?
No. For example, an Australian TGA listing documents Australian registration only; ask the clinic to confirm the specific product’s local Korean approval and indication.
Is Rejuran a hyaluronic-acid filler?
No. Classic Rejuran’s listed composition is PN. HB plus is a different formulation that also contains sodium hyaluronate and lidocaine.
Is it intended to add facial volume?
The manufacturer’s stated purpose is temporary improvement of facial wrinkles, not a promise of a specific volumizing result.
Which Rejuran product is right for me?
That depends on the area, skin characteristics, treatment goal, allergies and local approval; selection should follow an in-person assessment.
Does treatment hurt?
Injection discomfort is possible. HB plus contains lidocaine, but suitability still requires medical assessment.
How many sessions will I need?
There is no universal schedule. The clinician should determine it from the exact product, indication and local IFU.
Are results guaranteed?
No. The approved purpose is temporary wrinkle improvement; response and duration vary.
What is the difference between Rejuran, Rejuran i and Rejuran s?
They are separate products in one PN lineup, not grades of one product. PharmaResearch lists Classic, i and s individually and gives polynucleotide (PN) as the composition for each, but its public pages do not compare their viscosity or spread, so this guide ranks none of them. Ask the clinic why that specific product is proposed for your area and what its locally approved indication covers.
Rejuran HB plus vs regular Rejuran — what actually changes?
HB plus adds sodium hyaluronate and lidocaine to the PN base. For the PN-only products the manufacturer lists polynucleotide alone, so this is a composition difference rather than a ranking. The extra ingredients matter most for allergy screening, so mention any hyaluronic-acid or lidocaine reaction before a product is chosen.
Is Rejuran the same thing as Sculptra?
No — Rejuran is PN-based and Sculptra contains poly-L-lactic acid (PLLA). Galderma’s Sculptra instructions for use describe administration as a series of treatments with a gradual, collagen-related effect, while Rejuran’s stated purpose is temporary improvement of facial wrinkles. The two are not interchangeable.
How long should I stay in Korea after Rejuran before flying home?
Settle that with the treating clinic before you book the return flight. The manufacturer pages reviewed for this guide publish no recovery timeline, so aftercare and review timing have to come from the clinic and the instructions for use supplied in Korea. Ask how to reach them once you leave, and keep the product name and treatment date — this guide’s sources cover manufacturer information and an Australian TGA registration only, so approval and follow-up care in your own country must be checked locally.
Who should not get Rejuran?
Eligibility is decided from your medical history and the local instructions for use. The manufacturer’s public pages reviewed here do not publish a complete contraindication list, so ask the clinic to show the document supplied with the product in Korea. Raise your allergy history at consultation: the PN material is salmon-derived, and HB plus also contains hyaluronic acid and lidocaine.
What side effects does Rejuran have?
Injection pain is the only reaction documented on the manufacturer pages reviewed here. The manufacturer attributes it to PN’s molecular weight and viscosity, and no complete adverse-reaction list is published there, so ask for the one printed in the locally supplied instructions for use — another injectable’s list is not a substitute. Contact the treating clinic promptly for unexpected, worsening or persistent symptoms.
How do I compare Rejuran prices between clinics?
Compare like for like: exact product name, number of sessions and what is included. This guide does not publish prices, and a lower total can cover a different Rejuran product or fewer sessions. Ask each clinic to put the product name and session count in writing before you compare.
How Abijou works
We started in Gangnam in 2006 and the network now runs 17 branches across Korea. The line we work to is skin transformation woven into everyday life — care you can keep up with, rather than one dramatic change.
- Across the 17 branches in Seoul, Gyeonggi, Incheon and Busan: over 1,000 medical professionals and more than 350 certified medical devices
- Authentic products only, in appropriate amounts — the treatment is fitted to the condition, not to a package
- Prices are quoted from each branch’s published price list as it stands
Contact and location
- Phone
- 1544-0377
Free Consultation
Booking happens at the branch
There is no inquiry form on this page. Once you have picked a branch above, open that branch’s site or the official reservation center and choose a time yourself.
- No deposit and no online prepayment — everything is paid at the visit
- Per-treatment prices are published for each branch on the official reservation center
- English, Japanese and Chinese are supported alongside Korean