Injectable skin-quality guide

LIZNE PN Skin Booster

LIZNE is a PN (polynucleotide) skin booster that the clinic describes as injecting active ingredients into the skin layers; the maker, Juventa Healthcare, announced it as a Class 4 medical device. This guide separates what the maker says from what the clinic says.

Published Last updated Medically reviewed by Duk-ha Kim
Maker
Juventa Healthcare (per its own announcement)
Main material
Polynucleotide (PN)
Clinic-described anaesthesia
Topical numbing cream
Clinic-described session time
About 20–30 minutes

What is LIZNE?

LIZNE is a PN-based skin booster. The clinic describes the treatment as injecting active ingredients into the skin layers to support the skin environment, and notes that the feel of the result differs between individuals.

Sources: Abijou reservation centre — LIZNE PN skin booster guideDailypharm — Juventa Healthcare LIZNE launch report (trade press, company announcement)

Who makes LIZNE and what is PN?

Juventa Healthcare announced LIZNE as a skin booster whose main ingredient is polynucleotide (PN), DNA fragments sourced from salmon-family fish. PN is the product’s defining material, which is why LIZNE is discussed in the same breath as other PN products rather than hyaluronic-acid boosters.

Sources: Dailypharm — Juventa Healthcare LIZNE launch report (trade press, company announcement)

What did the maker announce about its regulatory class?

In its launch announcement, reported by Dailypharm, the company described LIZNE as a Class 4 medical device and said its raw material is produced domestically. This is company-announced information from trade press; ask the clinic to show the product documentation for the exact syringe used.

Sources: Dailypharm — Juventa Healthcare LIZNE launch report (trade press, company announcement)

What are the steps of a LIZNE session?

The clinic lists five steps: consultation and skin assessment, cleansing with topical numbing cream, injection of the active ingredient into the skin layers, soothing care with aftercare instructions, then a return to daily activities.

Sources: Abijou reservation centre — LIZNE PN skin booster guide

Is numbing used for LIZNE?

Yes. The clinic’s guide describes a topical numbing cream applied after cleansing. It describes discomfort as mild and varying from person to person.

Sources: Abijou reservation centre — LIZNE PN skin booster guide

How long does one session take?

The clinic gives about 20 to 30 minutes for a session. That figure is the clinic’s scheduling guide and includes the preparation steps listed above.

Sources: Abijou reservation centre — LIZNE PN skin booster guide

How often is LIZNE repeated?

The clinic describes several sessions at two- to four-week intervals, followed by maintenance sessions. This is the clinic’s own course design, not a figure taken from the maker.

Sources: Abijou reservation centre — LIZNE PN skin booster guide

How long does the effect last?

This page carries no duration measurement for LIZNE in either direction. The two- to four-week spacing is the clinic’s scheduling guidance for a course, not a study of how long a visible change lasts, and the maker announcement reviewed here does not state a duration either. What is worth asking is what the maintenance schedule is based on: an interval the clinic recommends regardless of how the skin looks, or an observed pattern of the effect fading. Also ask the clinic to separate any change they expect from the small marks that can appear in the first day or two after injection, since the two are easy to confuse when you judge the result.

Sources: Abijou reservation centre — LIZNE PN skin booster guideDailypharm — Juventa Healthcare LIZNE launch report (trade press, company announcement)

What does downtime and aftercare look like?

The clinic describes recovery as minimal, with tiny injection marks possible for one to two days, and gives soothing care and post-treatment instructions at the end of the visit. Follow the written instructions the clinic hands you.

Sources: Abijou reservation centre — LIZNE PN skin booster guide

What should you raise before treatment?

Because LIZNE’s PN is described as salmon-family derived, mention any fish allergy, plus current medication, pregnancy and skin conditions at the consultation. Eligibility is a clinician’s decision after assessment.

Sources: Dailypharm — Juventa Healthcare LIZNE launch report (trade press, company announcement)Abijou reservation centre — LIZNE PN skin booster guide

How does the clinic position LIZNE against Rejuran Healer and exosome?

The clinic’s guide frames LIZNE as aimed at skin texture and elasticity, Rejuran Healer at regeneration and texture, and exosome treatments at regeneration and soothing. That is the clinic’s own framing, not a head-to-head study; the products are made by different companies.

Sources: Abijou reservation centre — LIZNE PN skin booster guide

Medical care at Abijou

Care is provided by the medical team at the branch you select. These clinicians lead the three branches linked from this guide; confirm the doctor assigned to your visit with that branch.

Duk-ha Kim Chief MD, Gangnam

Chief MD, Gangnam

Duk-ha Kim

The trust our patients have placed in this clinic was built on conviction and principle. We intend to hold to both, unchanged, through the next hundred years.

Cheol-su Yoon Chief MD, Myeongdong

Chief MD, Myeongdong

Cheol-su Yoon

I want to be thinking about how the patient feels right up to the last moment of the procedure.

Jae-wook Kim Chief MD, Hongdae

Chief MD, Hongdae

Jae-wook Kim

I will give my best with the attentiveness to catch even the smallest change.

Listed branch medical team — not a medical-review byline for this article.

Frequently asked questions

What is LIZNE in simple terms?

A polynucleotide (PN) skin booster from Juventa Healthcare. The clinic describes the procedure as injecting active ingredients into the skin layers.

Who is the maker of LIZNE?

Juventa Healthcare, according to its own launch announcement reported in trade press.

Is LIZNE a hyaluronic-acid booster?

The announced main ingredient is polynucleotide (PN), not hyaluronic acid. Ask the clinic for the exact product composition of the syringe it uses.

Where does the PN in LIZNE come from?

The company announced that it is extracted from salmon-family fish and produced domestically in Korea.

Is LIZNE a medical device?

The company announced it as a Class 4 medical device. Treat that as company-announced and ask the clinic to show the product documentation.

Is a numbing cream used?

Yes, the clinic describes a topical numbing cream after cleansing.

Does LIZNE hurt?

The clinic describes the discomfort as mild and varying between people.

How long is one LIZNE session?

The clinic gives about 20 to 30 minutes including preparation.

How many sessions and how far apart?

The clinic describes several sessions at two- to four-week intervals, then maintenance. The exact plan is set at consultation.

Is there downtime after LIZNE?

The clinic describes it as minimal, with tiny injection marks possible for one to two days.

Can I go back to normal activities the same day?

The clinic lists a return to daily activities as the last step of the visit, after soothing care and instructions. Ask about makeup and exercise specifically.

Who should avoid LIZNE?

Eligibility is a clinician’s decision. Mention fish allergy, medication, pregnancy and skin conditions at the consultation.

Is LIZNE the same as Rejuran Healer?

No. They are different products from different makers, both described as PN-based. The clinic frames their aims differently, but it is not a head-to-head comparison.

Are LIZNE results guaranteed?

No. The clinic notes that results depend on the product and on individual skin condition.

How do I compare LIZNE offers between clinics?

Compare the exact product name, syringe volume, number of sessions and what is included. This guide publishes no prices; ask each clinic to write them down.

How Abijou works

We started in Gangnam in 2006 and the network now runs 17 branches across Korea. The line we work to is skin transformation woven into everyday life — care you can keep up with, rather than one dramatic change.

  • Across the 17 branches in Seoul, Gyeonggi, Incheon and Busan: over 1,000 medical professionals and more than 350 certified medical devices
  • Authentic products only, in appropriate amounts — the treatment is fitted to the condition, not to a package
  • Prices are quoted from each branch’s published price list as it stands

Contact and location

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Free Consultation

Booking happens at the branch

There is no inquiry form on this page. Once you have picked a branch above, open that branch’s site or the official reservation center and choose a time yourself.

  • No deposit and no online prepayment — everything is paid at the visit
  • Per-treatment prices are published for each branch on the official reservation center
  • English, Japanese and Chinese are supported alongside Korean
LIZNE PN Skin BoosterContact & booking