Chief MD, Gangnam
Duk-ha Kim
The trust our patients have placed in this clinic was built on conviction and principle. We intend to hold to both, unchanged, through the next hundred years.
Seoul
Liquid PCL injectable guide
GOURI is an injectable made by the Korean manufacturer DEXLEVO, described on its own product page as “the 1st liquid type PCL (Polycaprolactone) injectable.” PCL is a distinct polymer from the PLLA used in Sculptra and the PDO used in ULTRACOL 200 — three different materials that happen to share the same “collagen stimulator” marketing category.
GOURI is an injectable made by the Korean manufacturer DEXLEVO. On its own product page, DEXLEVO describes GOURI as “the 1st liquid type PCL (Polycaprolactone) injectable,” built on a formulation approach the company names CESABP.

Sources: DEXLEVO — GOURI product page, stated material and technology
PCL stands for polycaprolactone, a biodegradable synthetic polymer. DEXLEVO’s own product page places GOURI specifically in a liquid form, distinct from the solid microparticle or microsphere forms other manufacturers use for their own collagen-stimulator products. This description comes from the manufacturer; this page does not independently test the product.
Sources: DEXLEVO — GOURI product page, stated material and technology
DEXLEVO names its formulation technology CESABP — Collagen Enabled Solubilized Active and Biodegradable Polymer, per the company’s own wording. This is the manufacturer’s name for its own formulation approach, not an independent certification of a biological effect.
Sources: DEXLEVO — GOURI product page, stated material and technology
DEXLEVO is the South Korean manufacturer of GOURI. According to the company’s own milestone page, it obtained GMP and ISO13485 certification in 2015.
Sources: DEXLEVO — company milestones including certification history
DEXLEVO’s own milestone page lists 2021 as the year it obtained CE marking, following the 2015 GMP and ISO13485 certification. These are manufacturing-quality and EU market-access markers stated by the company; they are not a statement about a specific treatment outcome.
Sources: DEXLEVO — company milestones including certification history
GOURI is marketed within the broader “collagen stimulator” injectable category — a marketing grouping that also includes products made of entirely different materials. That shared label describes a category, not a single shared substance, so ask for the exact product name and material rather than assuming the category name tells you what is inside the syringe.
Sources: DEXLEVO — GOURI product page, stated material and technology
PCL (polycaprolactone), PLLA (poly-L-lactic acid) and PDO (polydioxanone) are three separate polymer materials. GOURI’s stated material is liquid-type PCL. Other products grouped in the same broad injectable category state PLLA or PDO instead. Because the three come from different chemical families, one material’s behavior should not be assumed to describe another.
Sources: DEXLEVO — GOURI product page, stated material and technology
The specific polymer a product is made from affects how it breaks down in tissue and what an emergency-response plan should assume if a complication occurs. Because PCL, PLLA and PDO are different substances, a degradation timeline or complication-response approach documented for one material should not be carried over to another. Confirming the exact product and material is where that conversation starts.
Sources: DEXLEVO — GOURI product page, stated material and technology
In 2021, the FDA’s Center for Devices and Radiological Health commissioned ECRI to run a systematic literature review of polycaprolactone. The review rates the evidence on local reactions to PCL-based sutures as “low quality” — reporting that comparator groups existed in the identified studies, but that results were inconsistent across them.
No. The 2021 review evaluates polycaprolactone as a material across the literature its authors identified — it does not test or evaluate GOURI or any other single product. The review’s own authors state that no study looked at PCL from a material standpoint on its own, describing this as a gap left for future research rather than a settled finding.
The review examined 86 surveillance reports connected to PCL-based devices. Of those, 48 involved sutures, and 42 of those 48 suture reports described device failure or malfunction.
The review reports zero studies describing systemic reactions to PCL. Read alongside the “low quality” rating for local-reaction evidence and the surveillance breakdown above, the authors present PCL as a material whose research base is still developing rather than one with an established systemic-safety record.
DEXLEVO’s own product page describes GOURI as a biodegradable, liquid-type PCL polymer, but neither of the two DEXLEVO pages used as sources here states a degradation timeline or a duration figure for the result. What is documented is that PCL, PLLA and PDO are three separate substances that break down differently once injected, so how long a result lasts tracks the specific material and formulation used — not the shared “collagen stimulator” category name. Ask the clinic what source backs any duration figure it quotes for the exact product it plans to use.
Sources: DEXLEVO — GOURI product page, stated material and technology
Injection depth and the specific tissue layer are treatment-planning details that vary by area and by product, and DEXLEVO’s own materials describe GOURI by material and technology rather than by a fixed depth for every case. Ask the treating clinic which layer is planned for your area and why, rather than assuming one depth applies across every “collagen stimulator” product.
Sources: DEXLEVO — GOURI product page, stated material and technology
Nodules are a reaction documented for injectables in this broader category on this site’s own sourced pages, and the review of PCL as a material found its evidence on local reactions to be of “low quality” with inconsistent results across studies. Ask the clinic, before treatment, how a nodule would be assessed, when you would need to return, and what the escalation plan is if it does not resolve.
Confirm the exact product name and manufacturer printed on the box, the material (liquid-type PCL, per DEXLEVO), the planned injection depth and tissue layer, and the clinic’s procedure if a nodule appears. Also ask the clinic to name the material of any other “collagen stimulator” product it offers, since PCL, PLLA and PDO are different substances even when marketed under the same category name.
Sources: DEXLEVO — GOURI product page, stated material and technology
These three names describe different polymer materials, each stated by a different manufacturer for its own product. Compare the material identity below before assuming a shared marketing category means a shared substance.
| Material | Full chemical name | Stated for | Head-to-head study cited here |
|---|---|---|---|
| PCL | Polycaprolactone | GOURI, per DEXLEVO’s own product page | None — see notice |
| PLLA | Poly-L-lactic acid | Other collagen-stimulator products on this site, per their own labeling | None — see notice |
| PDO | Polydioxanone | Other collagen-stimulator products on this site, per their own labeling | None — see notice |
This table names the material each manufacturer states for its own product. It is not a performance or safety ranking, and no study comparing PCL, PLLA and PDO head-to-head is cited on this page.
Sources: DEXLEVO — GOURI product page, stated material and technologyECRI review commissioned by FDA CDRH (2021) — polycaprolactone material performance and safety profile
Care is provided by the medical team at the branch you select. These clinicians lead the three branches linked from this guide; confirm the doctor assigned to your visit with that branch.
Chief MD, Gangnam
The trust our patients have placed in this clinic was built on conviction and principle. We intend to hold to both, unchanged, through the next hundred years.
Chief MD, Myeongdong
I want to be thinking about how the patient feels right up to the last moment of the procedure.
Chief MD, Hongdae
I will give my best with the attentiveness to catch even the smallest change.
Listed branch medical team — not a medical-review byline for this article.
GOURI is an injectable made by the Korean manufacturer DEXLEVO. The company’s own product page describes it as “the 1st liquid type PCL (Polycaprolactone) injectable,” built on a technology it names CESABP.
It means the stated material is polycaprolactone (PCL) in a liquid form, according to DEXLEVO’s own product page — distinct from the solid microparticle or microsphere forms other manufacturers use for products in the same broad marketing category.
CESABP is DEXLEVO’s own name for GOURI’s formulation technology, which the company defines as Collagen Enabled Solubilized Active and Biodegradable Polymer. It is the manufacturer’s own technology name, not an independent certification.
GOURI is made by DEXLEVO, a South Korean manufacturer. According to the company’s own milestone page, DEXLEVO obtained GMP and ISO13485 certification in 2015 and CE marking in 2021.
No. GOURI’s stated material is liquid-type PCL (polycaprolactone); Sculptra’s material is PLLA (poly-L-lactic acid), a different polymer family. Confirm the exact product and material rather than assuming a shared “collagen stimulator” label means a shared substance.
No. GOURI’s stated material is liquid-type PCL (polycaprolactone); ULTRACOL 200’s stated material is PDO (polydioxanone), a different polymer family. The two are not interchangeable simply because both fall under the same broad marketing category.
No. The category name covers products stated to be made of PCL, PLLA and PDO — three separate polymer materials from different manufacturers. Ask for the exact product name and material rather than relying on the category label.
Yes. In 2021, the FDA’s Center for Devices and Radiological Health commissioned ECRI to conduct a systematic literature review of polycaprolactone. It rates the evidence on local reactions to PCL-based sutures as “low quality,” citing inconsistent results across the studies it reviewed.
No. The review evaluates PCL as a material across the literature its authors identified; it does not test or evaluate GOURI or any other specific product. Its authors state that no study looked at PCL from a material standpoint on its own.
The review reports zero studies describing systemic reactions to PCL. Its authors present this, together with the “low quality” rating on local reactions, as an area left for future research rather than a settled safety finding.
It examined 86 surveillance reports connected to PCL-based devices, of which 48 involved sutures. Of those 48 suture reports, 42 described device failure or malfunction.
This site’s own Sculptra and Radiesse pages discuss erythema, bruising and nodules for their respective materials, each with its own cited source. This page does not restate those figures for PCL; ask the clinic which reaction data applies to the specific product proposed to you.
Ask the clinic, before treatment, how a nodule would be assessed, how quickly you could be seen, and what the escalation plan is if it does not resolve on its own. Nodules are a documented reaction across this broader injectable category, and PCL’s own evidence review found local-reaction data to be of “low quality” with inconsistent results.
Confirm the exact product name and manufacturer printed on the box, that the stated material is liquid-type PCL, the planned injection depth and tissue layer, and the clinic’s procedure if a nodule appears. If the clinic offers other “collagen stimulator” products, ask for each one’s material by name, since PCL, PLLA and PDO are not the same substance.
We started in Gangnam in 2006 and the network now runs 17 branches across Korea. The line we work to is skin transformation woven into everyday life — care you can keep up with, rather than one dramatic change.
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